¡Buenos dias chiquitos! Before you leave today, don’t forget to enter the Vital Sox Compression Sleeve / Arm Warmer giveaway! Closes on WEDNESDAY.
Last week, one of my very best friends asked me about taking over the counter medications before a race. She traveled to the land of the Canuks to race Ironman Canada (which was YESTERDAY!!), and was curious if anything she might take would interfere with her race day. With the amount of time one commits to training for an iron distance race, I would definitely agree that you don’t want an OTC medication (or any medication for that matter) to be your downfall. If my race turns into a nightmare, I want it to be because I was undertrained, overtrained, unprepared for the course/weather/competition/whatever. I do NOT want it to be because I took too many Naproxen.
So of course, she innocently asks me a sports science question. And I get excited and respond with a novel. I’ve done some editing of our emails to make sure all bases are covered, and with that I think we’re ready to go!

There are two general categories of meds an athlete would take pre-race: those that cause some sort of anti-inflammatory reaction // and // those that don’t.
Most of you have probably heard the term NSAIDS – non-steroidal anti-inflammatory drugs. You don’t really need to remember the whole thing – just that the NSAID stands for anti-inflammatory. NSAIDS work to reduce inflammation in the body, help prevent blood clots (thin the blood), can reduce fevers, and blocks the COX enzymes (refrain from jokes – it stands for cyclooxygenase). The COX enzyme is responsible for prostaglandin synthesis, which in turn contributes to inflammation, pain, and fever. We could go into the science and chemistry, but I don’t think that’s what you’re here for.
Common medications in this category include:
- Aspirin
- Ibuprofin (Advil, Motrin, Midol, Nuprin)
- Ketoprofen (Orudis-KT)
- Naproxen Sodium (Naproxen, Aleve, Anaprox, Naprelan)
- Celecoxib (generic of Celebrex. Rx only)
Then there is the category that does not cause an anti-inflammatory reaction. Because inflammation is such a big component of sports injuries… athletes are much less likely to take these on a whim. (Unless of course you were unaware that Tylenol and Advil won’t do the same things for you… in which case, keep on readin’.)
Again, a common [but incomplete] list would include:
- Acetaminophen (Tylenol)
- opiate agonists (Vicodin, morphine, codeine. Lets hope we’re talkin’ Rx only…)
- local anesthetics
There are a few that get complicated because they’re multi-ingredient pain killers… Tylenol No. 3 (300 mg acetaminophen, 30 mg codeine), Tylox and Percocet (acetaminophen and oxycodone – different strength combinations), Combunox (400 mg ibuprofen, 5 mg oxycodone), Vicoprofen (200 mg ibuprofen, 7.5 mg hydrocodone). Unless you’re taking any of those or extra curious, I wont go into it. However, I will strongly advocate that everyone should discuss everything they’re taking with their doctor – prescription, OTC, vitamins, supplements, the isht you buy at GNC – everything. It might be fine to take one medication on it’s own, but if your doctor doesn’t know you’re also taking _____, you could be talkin’ trouble.
In terms of the effect on performance… the two basic terms to know are ergogenic (performance enhancing) and ergolytic (performance inhibiting). While you will certainly find articles and published research touting ergogenic effects of particular medications, the research is not consistent.
[... One little tangent that I need to throw out there: If you’re not racing pro or collegiate, chances are you’ll never be drug tested. But for the love of God, the sport, and your own health, build a better engine. Don’t inject it with rocket fuel. (Unless you’re talking about Roctane, in which case I fully approve. Pineapple orange please.) Dopers suck. ...]
The biggest thing an everyday athlete would want to watch out for is the [unintentional] heavy-handed use of Aspirin or NSAIDS. As with almost everything in life, moderation is key. Without splitting atoms here, they can affect kidney function -> affects hydration and plasma volume -> dilutes electrolytes -> increases risk of hyponatremia. Keep the M[oderation]-word in mind, make sure you’re supplementing your electrolytes in addition to your fuel stores, and really you should be just fine.
So much for a short explanation. When I can actually apply the stuff I’ve learned, I get a little carried away.
Reader Qs:
Do you typically pop an advil pre-race? Pre-training? Or are you one of those people that would rather pull a nail out of your foot with eyebrow tweezers than take medication for something? I am… or at least I used to be. After my less than pleasant encounter with poison ivy earlier this month, I think I’ve softened a bit. Prednisone might make you look like a blowfish, but it makes the itching go away. Thank you Gregor Mendel, Louis Pasteur, James Watson, Francis Crick, Alexander Fleming, and the many more who have contributed to modern medicine.
CONGRATULATIONS ON AN AMAZING IRONMAN CANADA FINISH C.C.!! CAN’T WAIT TO CATCH UP WITH YOU WHEN YOU GET HOME!
The end.
-E
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